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Comparative proteomic investigation of metastatic and non-metastatic osteosarcoma cells of human and canine origin

14 Sept 2017

Abstract excerpt

Osteosarcoma is the most common bone cancer in dogs and people. In order to improve clinical outcomes, it is necessary to identify proteins that are differentially expressed by metastatic cells. Membrane bound proteins are responsible for multiple pro-metastatic functions. Therefore characterizing the differential expression of membranous proteins between metastatic and non-metastatic clonal variants will allow...

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PMID: 28910304
DOI: 10.1371/journal.pone.0183930

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