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Article

ox-LDL induces coronary microvascular dysfunction via endoplasmic reticulum stress in HCMECs: the protection of propionate

2023-05-22

Abstract excerpt

Coronary microvascular dysfunction (CMD) is an important pathogenesis of various cardiovascular diseases. Lower endothelial nitric oxide synthase (eNOS) phosphorylation leads to reduced endothelium-derived relaxing factor nitric oxide (NO) generation, causing and accelerating CMD. Endoplasmic reticulum stress (ER stress) has been shown to reduce NO production in umbilical vein endothelial cells. Oxidized low-densi...

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Literature Corpus work
bc4c05c7-2f24-5fbb-a83e-27fd00775d0f
DOI
10.21203/rs.3.rs-2938237/v1
Open publication

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ox-LDL induces coronary microvascular dysfunction via endoplasmic reticulum stress in HCMECs: the protection of propionateDOI 10.21203/rs.3.rs-2938237/v1
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