Article
ox-LDL induces coronary microvascular dysfunction via endoplasmic reticulum stress in HCMECs: the protection of propionate
2023-05-22
Abstract excerpt
Coronary microvascular dysfunction (CMD) is an important pathogenesis of various cardiovascular diseases. Lower endothelial nitric oxide synthase (eNOS) phosphorylation leads to reduced endothelium-derived relaxing factor nitric oxide (NO) generation, causing and accelerating CMD. Endoplasmic reticulum stress (ER stress) has been shown to reduce NO production in umbilical vein endothelial cells. Oxidized low-densi...
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Identifiers and source
- Literature Corpus work
- bc4c05c7-2f24-5fbb-a83e-27fd00775d0f
- DOI
- 10.21203/rs.3.rs-2938237/v1
