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Dynamic monitoring of viral gene expression reveals rapid antiviral effects of CD8 T cells recognizing the HCMV-pp65 antigen

2023-07-12

Abstract excerpt

<h4>ABSTRACT</h4> Human Cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in immunocompromised transplant recipients. Immunotherapy with CD8 T cells specific for HCMV antigens presented on HLA class-I molecules is explored as strategy for long-term relief to such patients, but the antiviral effectiveness of T cell preparations cannot be efficiently predicted by available methods. Therefore, w...

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Literature Corpus work
bc41ea7d-d6dc-555a-a063-76f9213389f1
DOI
10.1101/2023.07.11.548645
Open publication

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Dynamic monitoring of viral gene expression reveals rapid antiviral effects of CD8 T cells recognizing the HCMV-pp65 antigenDOI 10.1101/2023.07.11.548645
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