Article

Immunotherapy drug target identification using machine learning and patient-derived tumour explant validation

2024-12-05

Abstract excerpt

<title>Abstract</title> <p> Immunotherapy has revolutionised cancer treatment, yet few patients respond clinically, necessitating alternative strategies that can benefit these patients. Novel immune-oncology targets can achieve this through bypassing resistance mechanisms to standard therapies. To address this, we introduce MIDAS, a multimodal graph neural network system for immune-oncology target discovery that...

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Literature Corpus work: bc00866d-7133-584b-ae42-b807234471a0
DOI: 10.21203/rs.3.rs-5499857/v1

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