Article

Lysinoalanine crosslinking is a conserved post-translational modification in the spirochete flagellar hook

2023-06-13

Abstract excerpt

Spirochete bacteria cause Lyme disease, leptospirosis, syphilis and several other human illnesses. Unlike other bacteria, spirochete flagella are enclosed within the periplasmic space where the filaments distort and push the cell body by action of the flagellar motors. We previously demonstrated that the oral pathogen Treponema denticola (Td) catalyzes the formation of covalent lysinoalanine (Lal) crosslinks betw...

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Literature Corpus work: bbe97ac5-7279-5b80-a58b-f32e18f0cabe
DOI: 10.1101/2023.06.13.544825

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