Article

Core–sheath coupling controls flagellar curvature and motility in <i>Leptospira</i>

2026-02-02

Abstract excerpt

Spirochete pathogens are among the most invasive bacteria known, causing syphilis, Lyme disease, and leptospirosis. Their tissue penetration depends on periplasmic flagellar filaments that, unlike other bacterial flagella, are encased in a spirochete-specific multi-protein sheath and deform the cell body into motile waves. How these filaments achieve the mechanical properties needed for invasive motility has remai...

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Literature Corpus work: 11c04ee0-ac8a-5305-8748-6abe7a797927
DOI: 10.64898/2026.02.02.703089

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