Article
A novel flagellar sheath protein, FcpA, determines filament coiling, translational motility and virulence for the Leptospira spirochete.
Molecular microbiology - 1 Aug 2016
Wunder Elsio A, Figueira Cláudio P, Benaroudj Nadia, Hu Bo, Tong Brian A, Trajtenberg Felipe, Liu Jun, Reis Mitermayer G, Charon Nyles W, Buschiazzo Alejandro, Picardeau Mathieu, Ko Albert I
Abstract excerpt
Leptospira are unique among bacteria based on their helical cell morphology with hook-shaped ends and the presence of periplasmic flagella (PF) with pronounced spontaneous supercoiling. The factors that provoke such supercoiling, as well as the role that PF coiling plays in generating the characteristic hook-end cell morphology and motility, have not been elucidated. We have now identified an abundant protein...
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