Article

Establishing Primary Adult Fibroblast Cultures From Rodents

2010-10-05

Abstract excerpt

The importance of using primary cells, rather than cancer cell lines, for biological studies is becoming widely recognized. Primary cells are preferred in studies of cell cycle control, apoptosis, and DNA repair, as cancer cells carry mutations in genes involved in these processes. Primary cells cannot be cultured indefinitely due to the onset of replicative senescence or aneuploidization. Hence, new cultures need...

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Cancer Cells and Metastasis

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Literature Corpus work: bbc8d1c2-39de-51bc-ae70-e0a978da9c6f
DOI: 10.3791/2033-v

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