Article

A population-scale map of human tandem repeat composition and mutation dynamics from long-read assemblies

2024-08-09

Abstract excerpt

Tandem repeats (TRs) are highly mutable genomic elements composed of repeated motifs that drive genetic diversity and contribute to disease. Due to limited resolution at population scale, their mutation dynamics are incompletely understood. Here, we present TRCompDB, a reference database constructed on 832 human genomes that annotates the compositional diversity and population structure for 4.4 million TR loci. Le...

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Literature Corpus work: 2255a49e-6a35-5e37-bb63-a02db6f6928d
DOI: 10.1101/2024.08.07.607105

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