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Integrating Methylome and Transcriptome Signatures Expands the Molecular Classification of the Pituitary Tumors

12 Dec 2022

Abstract excerpt

OBJECTIVE: To explore pituitary tumors by methylome and transcriptome signatures in a heterogeneous ethnic population. METHODS: In this retrospective cross-sectional study, clinicopathological features, methylome, and transcriptome were evaluated in pituitary tumors from 77 patients (61% women, age 12-72 years) followed due to functioning (FPT: GH-secreting n = 18, ACTH-secreting n = 14) and nonfunctioning...

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PMID: 36504388
DOI: 10.1210/clinem/dgac703

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