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Natural selection exerted by historical coronavirus epidemic(s): comparative genetic analysis in China Kadoorie Biobank and UK Biobank

2024-02-06

Abstract excerpt

<h4>Background</h4> Pathogens have been one of the primary sources of natural selection affecting modern humans. The footprints of historical selection events – “selective sweeps” – can be detected in the genomes of present-day individuals. Previous analyses of 629 samples from the 1000 Genomes Project suggested that an ancient coronavirus epidemic ∼20,000 years ago drove multiple selective sweeps in the ancestor...

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Literature Corpus work: bb441153-fee1-5a8e-afeb-a2903f32b8f9
DOI: 10.1101/2024.02.06.579075

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