Article

The Role of the BMPR2 pathway in Group-II Pulmonary Hypertension Secondary to Valve Heart Disease

2025-02-27

Abstract excerpt

BMPR2 is widely known to be key in the pathobiology of pulmonary arterial hypertension. Recently, data regarding pulmonary hypertension (PH) secondary to left-heart disease (LHD) have focused on inflammatory and proliferative pathways rather than classic hemodynamic scope but BMPR2 role is yet to be determined. In the current study, we assessed BMPR2 and its regulatory factor, SRSF2, in patients with PH due to val...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bb15a9b1-50eb-5575-8d0d-ebcf6612a204
DOI: 10.1101/2025.02.26.25321265

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Role of the BMPR2 pathway in Group-II Pulmonary Hypertension Secondary to Valve Heart DiseaseDOI 10.1101/2025.02.26.25321265Read

Significance of BMPR2 mutations in pulmonary arterial hypertension.Semantic proximity Read

BMPR-II biomarkers for testing therapeutic efficacy in pulmonary arterial hypertension –the StratosPHere 1 studySemantic proximity Read

Gene symbol: BMPR2. Disease: Pulmonary hypertension, primary.Semantic proximity Read

Bone morphogenetic protein signalling in pulmonary arterial hypertension: revisiting the BMPRII connectionSemantic proximity Read

Novel Advances in Modifying BMPR2 Signaling in PAHSemantic proximity Read

Restoring BMPRII functions in pulmonary arterial hypertension: opportunities, challenges and limitations.Semantic proximity Read

BMP9 regulates the endothelial secretome to drive pulmonary hypertensionSemantic proximity Read

Molecular mechanisms of pulmonary arterial hypertension: role of mutations in the bone morphogenetic protein type II receptor.Semantic proximity Read

Epigenetic Regulation of Pulmonary Arterial Hypertension-Induced Vascular and Right Ventricular Remodeling: New Opportunities?Semantic proximity Read

Recent advances in pulmonary arterial hypertensionSemantic proximity Read

Emerging Mechanistic Insights and Therapeutic Strategies for Pulmonary Arterial Hypertension: A Focus on Right Ventricular Dysfunction and Novel Treatment PathwaysSemantic proximity Read

The Genetics of Pulmonary Arterial Hypertension in the <i>Post‐BMPR2</i> EraSemantic proximity Read