Article

Peptides derived from plant virus VPg protein inhibit eIF4E oncogene

2018-04-10

Abstract excerpt

Viruses of the Potyviridae family have VPg protein covalently attached to the 5’ end of their linear RNA genome. The protein interacts with the host translation initiation factor eIF4E that occurs in plant cells in two isoforms, one being the preferable target of a given VPg, the remaining one still acting in host protein synthesis. In animal cells only one form of eIF4E is directly involved in protein synthesis....

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Literature Corpus work: baede07f-43cb-5ef2-aac7-3b95986f6a6a
DOI: 10.1101/298455

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