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Article

A Novel Functional Human Eukaryotic Translation Initiation Factor 4G

1 Jan 1998

Abstract excerpt

Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a cap-binding protein complex consisting of three subunits: eIF4E, eIF4A, and eIF4G. In yeast and plants, two related eIF4G species are encoded by two different genes. To date, however, only one functional eIF4G polypeptide, referred to here as eIF4GI, has been identified in mammals. Here we describe the discovery and functional characterization of...

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PMID: 9418880
DOI: 10.1128/mcb.18.1.334

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