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Article

Conserved Arginine of the Potyviridae Viral Genome-Linked Proteins (VPg) as a Key Determinant for eIF4E Binding.

International journal of molecular sciences - 4 Apr 2026

Kolesnikova Victoria V, Nikonova Ekaterina Yu, Nikonov Stanislav V, Mikhaylina Alisa O, Simis Ilia B, Andreitsev Vladimir V, Do Phat T, Nikonov Oleg S

Abstract excerpt

Plant viruses from the Potyviridae family have a significant impact on crop productivity worldwide. We conducted a bioinformatic analysis of the VPg sequences from several members of the Potyviridae family. All analyzed primary structures of VPg contain an invariant arginine, which, according to the model we proposed earlier, is located in the functionally important α1-α2 hairpin of the viral protein and forms a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41977459
DOI: 10.3390/ijms27073280
PMCID: PMC13073118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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