Article

SURFBAT: a surrogate family-based association test building on large imputation reference panels

2023-01-11

Abstract excerpt

Genotype-phenotype association tests are typically adjusted for population stratification using principal components that are estimated genome-wide. This lacks resolution when analysing populations with fine structure and/or individuals with fine levels of admixture. This can affect power and precision, and is a particularly relevant consideration when control individuals are recruited using geographic selection c...

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Literature Corpus work: bae90ef2-c940-54d7-8af1-5e105bafc603
DOI: 10.1101/2023.01.10.523404

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