Article
Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis.
PLoS computational biology - 1 May 2015
Tymoshenko Stepan, Oppenheim Rebecca D, Agren Rasmus, Nielsen Jens, Soldati-Favre Dominique, Hatzimanikatis Vassily
Abstract excerpt
Toxoplasma gondii is a human pathogen prevalent worldwide that poses a challenging and unmet need for novel treatment of toxoplasmosis. Using a semi-automated reconstruction algorithm, we reconstructed a genome-scale metabolic model, ToxoNet1. The reconstruction process and flux-balance analysis...
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