Article

Aerosol delivery of immunotherapy and Hesperetin-loaded nanoparticles increases survival in a murine lung cancer model

2024-08-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Studies have shown that flavonoids like Hesperetin, an ACE2 receptor agonist with antioxidant and pro-apoptotic activity, can induce apoptosis in cancer cells. ACE2 receptors are abundant in lung cancer cells. Here, we explored the application of Hesperetin bound to PLGA-coated nanoparticles (Hesperetin-nanoparticles, HNPs), and anti-CD40 antibody as an aerosol treatment for lu...

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Literature Corpus work: bab2c889-a126-59c3-9a83-17c1bc2753e4
DOI: 10.1101/2024.08.30.609714

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