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Article

Harnessing mIR-145 deficiency to modulate inflammation and prevent degeneration in a mouse model of multiple sclerosis

2024-12-18

Abstract excerpt

<title>Abstract</title> <p>Multiple sclerosis (MS) is a progressive inflammatory disease of the central nervous system (CNS) marked by myelin loss, which impairs nerve function. Current therapies fail to halt disease progression or prevent myelin and axonal degeneration. In this study, we explored the impact of miR-145 knockout in a murine model of experimental autoimmune encephalomyelitis (EAE), which mimics MS...

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Literature Corpus work
ba9b2c37-247f-549c-817b-23c984f31b40
DOI
10.21203/rs.3.rs-5462410/v1
Open publication

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Harnessing mIR-145 deficiency to modulate inflammation and prevent degeneration in a mouse model of multiple sclerosisDOI 10.21203/rs.3.rs-5462410/v1
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