Article

CpG-creating Mutations are Costly in Many Human Viruses

2019-07-25

Abstract excerpt

Mutations can occur throughout the virus genome and may be beneficial or deleterious. We are interested in mutations that yield a C next to a G, producing CpG sites. CpG sites are rare in eukaryotic and viral genomes. For the eukaryotes, it is thought that CpG sites are rare because they are prone to mutation when methylated. In viruses, we know less about why CpG sites are rare. A previous study in HIV suggested...

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Literature Corpus work: ba8da4da-f4fe-5080-b8c0-4cf2ab0e353a
DOI: 10.1101/702175

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