Article

4258Re-evaluating the genetic contribution of monogenic dilated cardiomyopathy

2019-10-01

Abstract excerpt

Abstract Background Dilated cardiomyopathy (DCM) is genetically heterogeneous, with >100 purported disease genes tested in clinical laboratories. However, many genes were originally identified based on candidate-gene studies that did not adequately account for background population variation. Here we define the frequency of rare variation in 2538 DCM patients across protein-coding regions of 56 commonly tested gen...

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Literature Corpus work: ba391a37-86c5-503b-82cf-df26e0d5847c
DOI: 10.1093/eurheartj/ehz745.0136

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