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Analyses of more than 60,000 exomes questions the role of numerous genes previously associated with dilated cardiomyopathy

17 Sept 2016

Abstract excerpt

Background Hundreds of genetic variants have been described as disease causing in dilated cardiomyopathy (DCM). Some of these associations are now being questioned. We aimed to identify the prevalence of previously DCM associated variants in the Exome Aggregation Consortium (ExAC), in order to identify potentially false-positive DCM variants. Methods Variants listed as DCM disease-causing variants in the Human...

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PMID: 27896284
DOI: 10.1002/mgg3.245

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