Article
Genetic architecture of dilated cardiomyopathy in Poland: variant distribution, clinical characteristics, and prognosis.
Polish archives of internal medicine - 29 Sept 2025
Chmielewski Przemysław, Truszkowska Grażyna, Kostrzewa Grażyna, Michalak Ewa, Stawiński Piotr, Kowalik Ilona, Minota Ilona, Leszek Przemysław, Mazurkiewicz Łukasz, Krzysztoń-Russjan Jolanta, Płoski Rafał, Bilińska Zofia T
Abstract excerpt
INTRODUCTION: Genetic variants are the leading cause of dilated cardiomyopathy (DCM). Data on genetic testing in DCM from Central European populations are scarce. OBJECTIVES: We sought to determine the genetic architecture of DCM in Poland and to assess its influence on patient clinical characteristics and prognosis. PATIENTS AND METHODS: The study included 280 DCM patients (mean [SD] age, 39 [13] y; 68% men) who...
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