Article

Salicylate increases fitness cost associated with MarA-mediated antibiotic resistance

2018-10-29

Abstract excerpt

Antibiotic resistance is generally associated with a fitness deficit resulting from the burden of producing and maintaining resistance machinery. This additional cost suggests that resistant bacteria will be outcompeted by susceptible bacteria in conditions without antibiotics. However, in practice this process is slow due in part to regulation that minimizes expression of these genes in the absence of antibiotics...

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Literature Corpus work: ba382872-26a6-51e5-a1f4-9119bc9e1508
DOI: 10.1101/454983

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