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Article

Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer.

Nucleic acids research - 18 Feb 2015

Sebestyén Endre, Zawisza Michał, Eyras Eduardo

Abstract excerpt

The determination of the alternative splicing isoforms expressed in cancer is fundamental for the development of tumor-specific molecular targets for prognosis and therapy, but it is hindered by the heterogeneity of tumors and the variability across patients. We developed a new computational method, robust to biological and technical variability, which identifies significant transcript isoform changes across...

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Source

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Identifiers

PMID: 25578962
DOI: 10.1093/nar/gku1392
PMCID: PMC4330360

Genes

MYH11
ABI1
CCND3
CTNND1
FBLN2
MITF
PPARG
PRDM1
RALGDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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