Article

Secretion Inhibition of CCL2 by Decorin in colorectal cancer tumor-associated macrophages and the synergistic therapeutic effect with PD-1inhibitor

2026-06-15

Abstract excerpt

<title>Abstract</title> <p>The mechanisms of occurrence and development of colorectal cancer (CRC) are highly complex and multifaceted, in which tumor-associated macrophages (TAMs) play a key role, and their changes in function and phenotype have a significant impact on tumor progression. The dysregulated expression of decorin (DCN) in colorectal cancer promotes the occurrence and development of colorectal cancer...

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Literature Corpus work: ba21846a-9b05-507a-b41b-4ba7e1f06e18
DOI: 10.21203/rs.3.rs-9679851/v1

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