Article

Apoptosis and Cancer

2016-11-18

Abstract excerpt

Cancer is a disease involving the abnormal accumulation of cells resulting from an imbalance of proliferation and programmed cell death. This review focuses on the mitochondrial apoptotic pathway, a mechanism of programmed cell death with particular relevance to cancer. Starting over 30 years ago, basic findings in model organisms have been combined with findings in clinical cytogenetics to uncover a family of pro...

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Identifiers and source

Literature Corpus work: b9ec99cd-90ab-5851-9895-e3669129e3dd
DOI: 10.1146/annurev-cancerbio-050216-121933

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