Article

An integrative model of leukocyte genomics and organ dysfunction in heart failure patients requiring mechanical circulatory support

2015-08-14

Abstract excerpt

<h4>Background</h4> The implantation of mechanical circulatory support (MCS) devices in heart failure patients is associated with a systemic inflammatory response, potentially leading to death from multiple organ dysfunction syndrome. Previous studies point to the involvement of many mechanisms, but an integrative hypothesis does not yet exist. Using time-dependent whole-genome mRNA expression in circulating leuk...

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Literature Corpus work: b9e8b285-a08c-5692-8fa7-1561722a365f
DOI: 10.1101/024646

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