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<i>In vitro</i> evolution of uropathogenic <i>Escherichia coli</i> to fosfomycin resistance in a 3D cultured human bladder microtissue model

2026-07-22

Abstract excerpt

In vitro studies of antimicrobial resistance (AMR) using laboratory growth media produce important, fundamental information. However, their inability to more closely replicate the in vivo environment limits the translational potential of this work. Here, we used a 3D cultured microtissue model which reflects the human bladder microenvironment to select for resistance to fosfomycin in two uropathogenic strains of...

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Literature Corpus work
b9e89949-956e-5a5f-b1f3-89aa251c7670
DOI
10.64898/2026.07.22.740011
Open publication

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