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A Machine Learning Approach Reveals CRISPR-Cas I-F as a Genomic Marker of Antibiotic Susceptibility in Uropathogenic <i>E. coli</i>

2025-10-14

Abstract excerpt

<h4>Background</h4> Antimicrobial resistance (AMR) in Escherichia coli is a critical global health challenge, particularly in urinary tract infections, where first-line treatments are increasingly compromised. While horizontal gene transfer (HGT) via mobile genetic elements is a major driver of AMR, the genomic factors that may constrain resistance gene acquisition remain underexplored. CRISPR-Cas systems, which...

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Literature Corpus work
a4c164ac-92e5-59bc-a67e-c6650b688045
DOI
10.1101/2025.10.13.681552
Open publication

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A Machine Learning Approach Reveals CRISPR-Cas I-F as a Genomic Marker of Antibiotic Susceptibility in Uropathogenic <i>E. coli</i>DOI 10.1101/2025.10.13.681552
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