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Article

Epigenetics and metabolism.

Circulation research - 13 Feb 2015

Keating Samuel T, El-Osta Assam

Abstract excerpt

The molecular signatures of epigenetic regulation and chromatin architectures are fundamental to genetically determined biological processes. Covalent and post-translational chemical modification of the chromatin template can sensitize the genome to changing environmental conditions to establish diverse functional states. Recent interest and research focus surrounds the direct connections between metabolism and...

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PMID: 25677519
DOI: 10.1161/CIRCRESAHA.116.303936

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