Article
Epigenetics and metabolism.
Circulation research - 13 Feb 2015
Keating Samuel T, El-Osta Assam
Abstract excerpt
The molecular signatures of epigenetic regulation and chromatin architectures are fundamental to genetically determined biological processes. Covalent and post-translational chemical modification of the chromatin template can sensitize the genome to changing environmental conditions to establish...
Topics
- Animals
- Chromatin Assembly and Disassembly
- DNA Methylation
- Energy Metabolism
- Epigenesis, Genetic
- Female
- Gene-Environment Interaction
- Genetic Predisposition to Disease
- Glucose
- Humans
- Lipid Metabolism
- Male
- Maternal Nutritional Physiological Phenomena
- Metabolic Diseases
- Nutritional Status
- Phenotype
- Pregnancy
- Prenatal Exposure Delayed Effects