Article

Long-read analysis of tetrameric microsatellites with vmwhere supports GGAA repeat length–dependent chromatin state association in Ewing sarcoma

2026-04-10

Abstract excerpt

Microsatellites are abundant genomic elements that contribute to genetic diversity and disease-associated regulatory variation. Although long-read sequencing enables accurate resolution of repetitive regions, computational methods for fully resolved microsatellite genotyping remain limited. Here, we introduce variant motif where (vmwhere), a computational framework for identifying, genotyping, decomposing, and vis...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b9632713-fda8-510f-a0da-cb85a2de55db
DOI: 10.64898/2026.04.08.717017

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Long-read analysis of tetrameric microsatellites with vmwhere supports GGAA repeat length–dependent chromatin state association in Ewing sarcomaDOI 10.64898/2026.04.08.717017Read

Hunting for microsatellite instability in long-read data with OwlSemantic proximity Read

Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding.Semantic proximity Read

ECHO: a nanopore sequencing-based workflow for (epi)genetic profiling of the human repeatomeSemantic proximity Read

ATaRVa: Analysis of Tandem Repeat Variation from Long-Read Sequencing dataSemantic proximity Read

MSIanalyzer: Targeted Nanopore Sequencing Enables Single Nucleotide Resolution Analysis of Microsatellite Instability Diversity.Semantic proximity Read

Reference-free microsatellite instability detection from tumor sequencing using intrasample variability modelingSemantic proximity Read

Comprehensive detection of genetic and epigenetic alterations in cancer using long reads with TumorLensSemantic proximity Read

Resolving the unsolved: Comprehensive assessment of tandem repeats at scaleSemantic proximity Read

VAMPIRE: Analyzing variation and motif pattern in tandem repeatsSemantic proximity Read

Analysis of somatic microsatellite indels identifies driver events in human tumors.Semantic proximity Read

High-fidelity, Large-scale Targeted Profiling of MicrosatellitesSemantic proximity Read

High-fidelity, large-scale targeted profiling of microsatellites.Semantic proximity Read