Article

Molecular Deconstruction of the Medullary Raphe Magnus in the rat: Transcriptional Responses to Repeated Seizures

2025-09-22

Abstract excerpt

Sudden Unexpected Death in Epilepsy (SUDEP) is a leading cause of death in patients with epilepsy and is thought to result from dysfunctional and/or failure of cardiorespiratory control systems. Post-mortem brainstem tissue analyses in human SUDEP cases point to reductions in markers of the brainstem serotonin (5-HT) system, which is known as a brainstem center that provides excitatory neuromodulation. We have pre...

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Literature Corpus work: b909072a-4d5f-5356-b438-721ef4666556
DOI: 10.1101/2025.09.22.677744

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