Article

MRI of <i>Capn15</i> knockout mice and analysis of Capn 15 distribution reveal possible roles in brain development and plasticity

2019-09-10

Abstract excerpt

The Small Optic Lobe (SOL) family of calpains are intracellular cysteine proteases that are expressed in the nervous system and play an important role in neuronal development in both Drosophila , where loss of this calpain leads to the eponymous small optic lobes, and in mouse and human, where loss of this calpain leads to eye anomalies. Some human individuals with biallelic variants in CAPN15 also have developme...

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Literature Corpus work: b907f098-14ff-5404-89d9-18683f8eef20
DOI: 10.1101/763888

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