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Article

Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function.

Scientific reports - 16 Jan 2020

Findlay Amy S, McKie Lisa, Keighren Margaret, Clementson-Mobbs Sharon, Sanchez-Pulido Luis, Wells Sara, Cross Sally H, Jackson Ian J

Abstract excerpt

Fam151b is a mammalian homologue of the C. elegans menorin gene, which is involved in neuronal branching. The International Mouse Phenotyping Consortium (IMPC) aims to knock out every gene in the mouse and comprehensively phenotype the mutant animals. This project identified Fam151b homozygous knock-out mice as having retinal degeneration. We show they have no photoreceptor function from eye opening, as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31949211
DOI: 10.1038/s41598-019-57398-4
PMCID: PMC6965129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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