Article

Spatial transcriptomic profiling of human retinoblastoma

2024-02-08

Abstract excerpt

Retinoblastoma (RB) represents one of the most prevalent intraocular cancers in children. Understanding the tumor heterogeneity in RB is important to design better targeted therapies. Here we used spatial transcriptomic to profile human retina and RB tumor to comprehensively dissect the spatial cell-cell communication networks. We found high intratumoral heterogeneity in RB, consisting of 10 transcriptionally dist...

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Literature Corpus work: b8f5f8d5-af71-51b9-b86f-64ef9637e588
DOI: 10.1101/2024.02.05.578886

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