Article

Immune-Coagulation Dynamics in Severe COVID-19: Insights from Autoantibody Profiling and Transcriptomics

2025-03-17

Abstract excerpt

<h4>ABSTRACT</h4> Severe COVID-19 is characterized by immune dysregulation and coagulation abnormalities, leading to complications such as thromboembolism and multi-organ failure. This study explores the relationship between autoantibodies targeting coagulation-related factors and gene expression in severe COVID-19. Whole-blood transcriptomics revealed upregulation of coagulation-related genes, including VWF and...

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Literature Corpus work: 1b6dc55f-d1fb-530c-abd5-3b82c33de765
DOI: 10.1101/2025.03.14.643398

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