Article

Predictive mutagenesis of prolyl endopeptidase from non-pathogenic acidophilic bacteria for gliadin catalysis

2023-04-12

Abstract excerpt

The enzyme prolyl endopeptidase is a member of serine peptidase group belonging to the MEROPS peptidase family S9 of clan SC. It is popularly known for its preferential cleavage of small peptides usually 30 amino acid long at the carboxyl end of proline residues. This characteristic cleavage property makes prolyl endopeptidase a therapeutic in treating gluten allergy which is triggered by 33 amino acid long (gliad...

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Literature Corpus work: b895a49c-7803-5072-b49d-1dda8059dda8
DOI: 10.21203/rs.3.rs-2788341/v1

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