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Vesicular stomatitis virus chimeras expressing the Oropouche virus glycoproteins elicit protective immune responses in mice

2021-02-19

Abstract excerpt

Oropouche virus (OROV) infection of humans is associated with a debilitating febrile illness that can progress to meningitis or encephalitis. First isolated from a forest worker in Trinidad and Tobago in 1955, the arbovirus OROV has since been detected throughout the Amazon basin with an estimated 500,000 human infections. Like other members of the family Peribunyaviridae , the viral genome exists as 3 single-str...

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Literature Corpus work
b852aa3d-a64f-5458-aabb-7a523e85d532
DOI
10.1101/2021.02.19.432025
Open publication

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Vesicular stomatitis virus chimeras expressing the Oropouche virus glycoproteins elicit protective immune responses in miceDOI 10.1101/2021.02.19.432025
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