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Cancer stem cell plasticity and its implications in the development of new clinical approaches for oral squamous cell carcinoma

17 Aug 2022

Abstract excerpt

Oral squamous cell carcinoma (SCC) represents a major worldwide disease burden, with high rates of recurrence and metastatic spread following existing treatment methods. Populations of treatment resistant cancer stem cells (CSCs) are well characterised in oral SCC. These populations of CSCs engage the cellular programme known as epithelial mesenchymal transition (EMT) to enhance metastatic spread and therapeutic...

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PMID: 35985402
DOI: 10.1016/j.bcp.2022.115212

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