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Genomic instability and biofilm determinants in <i>Streptococcus mutans</i> : insights from a sequence-defined arrayed transposon library

2026-03-26

Abstract excerpt

Streptococcus mutans is a primary architect of dental caries, utilizing complex genetic networks to build resilient, acid-producing biofilms. While pooled screens (Tn-seq) have identified important fitness factors, they often fail to capture extracellular or moderate-effect determinants due to community-level masking. Therefore, to study biofilm phenotypes, we constructed a comprehensive arrayed library of 9,216 m...

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Literature Corpus work
b7ea1751-3e17-53a5-a8c6-e4ef54c1fe18
DOI
10.64898/2026.03.25.714184
Open publication

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Genomic instability and biofilm determinants in <i>Streptococcus mutans</i> : insights from a sequence-defined arrayed transposon libraryDOI 10.64898/2026.03.25.714184
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