Article

ATP-Citrate lyase fuels axonal transport across species

2020-07-07

Abstract excerpt

Microtubule (MT)-based transport is an evolutionary conserved processed finely tuned by posttranslational modifications. Among them, α-tubulin acetylation, which is catalyzed by the α-tubulin N-acetyltransferase 1, Atat1, promotes the recruitment and processivity of molecular motors along MT tracks. However, the mechanisms that controls Atat1 activity remains poorly understood. Here, we show that a pool of vesicul...

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Literature Corpus work: b7983779-69fd-5931-bb99-935294781073
DOI: 10.1101/2020.07.07.192096

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