Article

Convergent synthesis and biological evaluation of vitamin D analogues as potential anticancer agents

2016-01-15

Abstract excerpt

Synthetic analogs of 1alpha,25-dihydroxycholecalciferol [1alpha,25-(OH)2D3] and 1alpha,25-dihydroxyergocalciferol [1alpha,25-(OH)2D2] have long been considered as key regulators of calcium and phosphate homeostasis. These analogs have been recently investigated as potential therapeutics against a number of pathological states, including metabolic, dermatological, immune and hyperproliferative diseases. Analogues o...

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Literature Corpus work: b7648002-efaa-567d-8418-0314c93b03dd
DOI: 10.7287/peerj.preprints.1653v1

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