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Identification of aging-related biomarkers and immune infiltration characteristics in osteoarthritis based on bioinformatics analysis and machine learning

12 Jul 2023

Abstract excerpt

Background: Osteoarthritis (OA) is a degenerative disease closely related to aging. Nevertheless, the role and mechanisms of aging in osteoarthritis remain unclear. This study aims to identify potential aging-related biomarkers in OA and to explore the role and mechanisms of aging-related genes and the immune microenvironment in OA synovial tissue. Methods: Normal and OA synovial gene expression profile...

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Bioinformatics and Genomic Networks
Ferroptosis and cancer prognosis
Osteoarthritis Treatment and Mechanisms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37503333
DOI: 10.3389/fimmu.2023.1168780

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