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Article

Common Mechanism of SARS-CoV and SARS-CoV-2 Pathogenesis across Species

2021-05-14

Abstract excerpt

Sarbecovirus (CoV) infections, including Severe Acute Respiratory CoV (SARS-CoV) and SARS-CoV-2, are considerable human threats. Human GWAS studies have recently identified loci associated with variation in SARS-CoV-2 susceptibility. However, genetically tractable models that reproduce human CoV disease outcomes are needed to mechanistically evaluate genetic determinants of CoV susceptibility. We used the Collabor...

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Literature Corpus work
b702ad6d-354e-5332-babd-c2ccb6ddd33b
DOI
10.1101/2021.05.14.444205
Open publication

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