Article

High basal autophagic activity in the brain revealed by systemic quantitative analysis using GFP-LC3-RFP mice

2026-05-21

Abstract excerpt

<h4>Summary</h4> Autophagy is a fundamental intracellular degradation pathway with vital physiological functions. Although it is well known that autophagy is activated during starvation, the extent of basal autophagy remains unclear owing to challenges in measuring autophagic flux in vivo . In this study, we developed autophagy reporter (GFP–LC3–RFP) mice and quantified basal autophagic flux across tissues by co...

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Literature Corpus work: b6e0ad8b-6c51-56c1-bba2-7ae1f68d977c
DOI: 10.64898/2026.05.20.726446

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