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Multimodal single-cell analysis reveals the prognostic role of myeloid subpopulation–driven PI3K/AKT signaling in hepatocellular carcinoma

2025-10-28

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Hepatocellular carcinoma (HCC) represents a major global health burden, characterized by rising incidence, marked heterogeneity, and poor prognosis. Reliable biomarkers for prognostic stratification and therapeutic targeting remain urgently needed. <bold>Methods:</bold> We conducted an integrative multi-omics analysis by combining TCGA-LIHC bulk RNA-seq dat...

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Literature Corpus work
b6ca1351-f79d-507e-b19d-c18fddebe715
DOI
10.21203/rs.3.rs-7749421/v1
Open publication

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Multimodal single-cell analysis reveals the prognostic role of myeloid subpopulation–driven PI3K/AKT signaling in hepatocellular carcinomaDOI 10.21203/rs.3.rs-7749421/v1
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