Article

<i>Pseudomonas aeruginosa</i> co-opts host antibiotic metabolism by pyocyanin induction of cytochrome P450 enzymes

2026-07-27

Abstract excerpt

<h4>ABSTRACT</h4> The human opportunistic pathogen Pseudomonas aeruginosa produces copious quantities of the secondary metabolite pyocyanin (PYO). PYO has recently been shown to interact with the aryl hydrocarbon receptor (AhR), a transcription factor controlling expression of a number of genes, including the cytochrome P450 CYP1A family involved in fluoroquinolone antibiotic clearance. In this study, we investi...

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Literature Corpus work: b682e695-29ab-5fca-bcee-4b393656e473
DOI: 10.64898/2026.07.25.740721

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