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Metabolic reshaping drives novel melanin production from tryptophan in a cystic fibrosis <i>Pseudomonas aeruginosa</i> clinical isolate

2025-12-15

Abstract excerpt

Pseudomonas aeruginosa is a human opportunistic pathogen, capable of producing a wide range of metabolites, including pyomelanin. This pigment results from alterations in tyrosine catabolism. Melanin synthesis from tryptophan has never been reported in Pseudomonas . In this study, we describe a tryptophan-derived melanin in P. aeruginosa PAH, a strain that was isolated from a fibrocystic patient. PAH produced a...

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Literature Corpus work
6f725632-623e-522a-8d19-7d56d8edca6b
DOI
10.64898/2025.12.15.694361
Open publication

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Metabolic reshaping drives novel melanin production from tryptophan in a cystic fibrosis <i>Pseudomonas aeruginosa</i> clinical isolateDOI 10.64898/2025.12.15.694361
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