Article

2’-Fucosyllactose Inhibits Human Norovirus Replication in Human Intestinal Enteroids

2024-05-31

Abstract excerpt

<h4>ABSTRACT</h4> Human noroviruses (HuNoVs) are the leading cause of acute gastroenteritis worldwide. Currently, there are no targeted antivirals for the treatment of HuNoV infection. Histo-blood group antigens (HBGAs) on the intestinal epithelium are cellular attachment factors for HuNoVs; molecules that block the binding of HuNoVs to HBGAs thus have the potential to be developed as antivirals. Human milk oligo...

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Literature Corpus work: b640d7d4-0bbe-589d-a26b-289975258b1e
DOI: 10.1101/2024.05.30.596597

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